e6/ ITGB4BP (AA 141-245) 抗体 (AbBy Fluor® 750)
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- 抗原
- e6/ ITGB4BP
- 抗原表位
- AA 141-245
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human eIF6
- 亚型
- IgG
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-
- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- e6/ ITGB4BP
- 别名
- e6/ITGB4BP
- 背景
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Synonyms: b2gcn, B2GCN homolog, B4 integrin interactor, Binding protein of beta-4 integrin, CAB, e-6, E3A, E6, Eukaryotic translation initiation factor 3A, Eukaryotic translation initiation factor 6, 6_HUMAN, ITGB4BP, OK/SW-cl.27, p27 beta 4 integrin binding protein, p27BBP, p27BBP, RP4-614O4.1.
Background: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by Intergrin beta 4 binding protein binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding several different isoforms have been found for this gene.
- 基因ID
- 3692
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