DERL1 抗体 (AA 111-220) (AbBy Fluor® 750)
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- 抗原 See all DERL1 抗体
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
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抗原表位
- AA 111-220
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DERL1 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DERLIN-1
- 亚型
- IgG
- Top Product
- Discover our top product DERL1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
- 别名
- DERLIN-1 (DERL1 产品)
- 别名
- CG10908 antibody, Dmel\\CG10908 antibody, DDBDRAFT_0188135 antibody, DDBDRAFT_0266772 antibody, DDB_0188135 antibody, DDB_0266772 antibody, MGC84200 antibody, wu:fb09d07 antibody, wu:fb94d05 antibody, wu:fj92g12 antibody, zgc:55637 antibody, 1110021N07Rik antibody, AI195141 antibody, AW551338 antibody, Derlin-1 antibody, derlin-1 antibody, DER-1 antibody, DER1 antibody, RGD1311835 antibody, DERLIN-1 antibody, F17A13.150 antibody, F17A13_150 antibody, Derlin-1 antibody, derlin-1 antibody, derlin-1.1 antibody, hypothetical protein antibody, Der1-like domain family, member 1 antibody, derlin 1 antibody, derlin 1 L homeolog antibody, DERLIN-1 antibody, Der-1 antibody, EDI_023440 antibody, PTRG_01331 antibody, derl1 antibody, DERL1 antibody, derl1.L antibody, Derl1 antibody, DER1 antibody
- 背景
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Synonyms: Derlin1, Derlin1, Derlin 1, DER1, DER-1, DER 1, DERL1_HUMAN.
Background: Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.
- 基因ID
- 79139
- UniProt
- Q9BUN8
- 途径
- ER-Nucleus Signaling
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