Junctophilin 3 抗体 (Center)
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- 抗原 See all Junctophilin 3 (JPH3) 抗体
- Junctophilin 3 (JPH3)
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抗原表位
- Center
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Junctophilin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects JPH3 at center.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- JPH3 antibody was raised against a 18 amino acid peptide near the center of human JPH3.
- 亚型
- IgG
- Top Product
- Discover our top product JPH3 Primary Antibody
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anti-Junctophilin 3 (JPH3) (N-Term) antibody
JPH3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 3 (JPH3) (N-Term) antibodyJPH3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 3 (JPH3) (AA 549-578) antibodyJPH3 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB9251 unconjugated
anti-Junctophilin 3 (JPH3) (N-Term) antibodyJPH3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, Pig, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 3 (JPH3) (C-Term) antibodyJPH3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 3 (JPH3) (Middle Region) antibodyJPH3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Junctophilin 3 (JPH3)
- 别名
- Junctophilin-3 / JPH3 (JPH3 产品)
- 别名
- CAGL237 antibody, HDL2 antibody, JP-3 antibody, JP3 antibody, TNRC22 antibody, Jp3 antibody, fc26e06 antibody, si:ch211-255l14.9 antibody, wu:fc26e06 antibody, junctophilin 3 antibody, JPH3 antibody, Jph3 antibody, jph3 antibody
- 背景
- Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions. A repeat expansion in JPH3 is associated with Huntington disease-like 2. At least two isoforms of JPH3 are known to exist.Synonyms: JP3, Junctophilin type 3, TNRC22, Trinucleotide repeat-containing gene 22 protein
- 基因ID
- 57338
- NCBI登录号
- NP_065706
- UniProt
- Q8WXH2
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