Junctophilin 1 抗体 (C-Term)
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- 抗原 See all Junctophilin 1 (JPH1) 抗体
- Junctophilin 1 (JPH1)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Junctophilin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects JPH1.
- 交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- JPH1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human JPH1.
- 亚型
- IgG
- Top Product
- Discover our top product JPH1 Primary Antibody
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- 应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Junctophilin 1 (JPH1)
- Abstract
- JPH1 产品
- 别名
- JP-1 antibody, JP1 antibody, ENSMUSG00000054314 antibody, Jp1 antibody, bZ1M12.3 antibody, jph1 antibody, si:rp71-1m12.3 antibody, Jph1 antibody, junctophilin 1 antibody, junctophilin 1a antibody, junctophilin-1 antibody, JPH1 antibody, Jph1 antibody, jph1 antibody, jph1a antibody, LOC100547979 antibody
- 背景
- Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH1 is essential for stabilizing the T-tubule and SR membranes to form junctions and provide an environment for the assembly of receptors such as the ryanodine receptor type 1 (RyR1).Synonyms: JP1
- 基因ID
- 56704
- NCBI登录号
- NP_065698
- UniProt
- Q9HDC5
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