IL22 Receptor alpha 1 抗体 (N-Term)
-
- 抗原 See all IL22 Receptor alpha 1 (IL22RA1) 抗体
- IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
-
抗原表位
- N-Term
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IL22 Receptor alpha 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- IL-22 receptor antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Human IL-22 Receptor (N-Terminus) Peptide
- 亚型
- IgG
- Top Product
- Discover our top product IL22RA1 Primary Antibody
-
-
- 应用备注
-
ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 62 kDa band can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
-
- 抗原
- IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
- 别名
- IL22RA1 / IL22R (IL22RA1 产品)
- 别名
- IL22RA1 antibody, CRF2-9 antibody, IL22R antibody, IL22R1 antibody, 9130219A07Rik antibody, ENSMUSG00000073746 antibody, IL-22R antibody, Il22r antibody, RGD1559655 antibody, interleukin 22 receptor subunit alpha 1 antibody, interleukin 22 receptor, alpha 1 antibody, IL22RA1 antibody, Il22ra1 antibody
- 背景
- A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified (1-3). The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family (3,4). IL-22R forms a complex with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-a 2 (IL-22RA2), was identified very recently (5-7). IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.Synonyms: CRF2-9, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Interleukin-22 receptor subunit alpha-1, ZcytoR11
- 基因ID
- 58985
- UniProt
- Q8N6P7
-