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INSM1 抗体 (N-Term)

This anti-INSM1 antibody is a 兔 多克隆 antibody detecting INSM1 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN499952
发货至: 中国

Quick Overview for INSM1 抗体 (N-Term) (ABIN499952)

抗原

See all INSM1 抗体
INSM1 (Insulinoma-Associated 1 (INSM1))

适用

  • 17
  • 13
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 17
  • 1

克隆类型

  • 15
  • 3
多克隆

标记

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This INSM1 antibody is un-conjugated

应用范围

  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody reacts to IA-1.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    IA-1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human IA-1.

    亚型

    IgG
  • 应用备注

    ELISA. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    INSM1 (Insulinoma-Associated 1 (INSM1))

    别名

    INSM1 / IA1

    背景

    IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100 % of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.Synonyms: Insulinoma-associated protein 1, Zinc finger protein IA-1

    基因ID

    3642

    NCBI登录号

    NP_002187

    UniProt

    Q01101
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