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GRIK4 抗体 (N-Term)

GRIK4 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499930
发货至: 中国
  • 抗原 See all GRIK4 抗体
    GRIK4 (Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4))
    抗原表位
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 18
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 16
    • 2
    克隆类型
    • 17
    • 1
    多克隆
    标记
    • 14
    • 2
    • 1
    • 1
    This GRIK4 antibody is un-conjugated
    应用范围
    • 14
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Grik4 antibody was raised against a 14 amino acid peptide near the amino terminus of the human Grik4.
    亚型
    IgG
    Top Product
    Discover our top product GRIK4 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    GRIK4 (Glutamate Receptor, Ionotropic, Kainate 4 (GRIK4))
    别名
    Glutamate Receptor KA1 / GRIK4 (GRIK4 产品)
    别名
    GRIK4 antibody, ka1 antibody, eaa1 antibody, EAA1 antibody, GRIK antibody, GluK4 antibody, KA1 antibody, 6330551K01Rik antibody, GluRgamma1 antibody, KA-1 antibody, glutamate receptor, ionotropic, kainate 4 antibody, glutamate ionotropic receptor kainate type subunit 4 antibody, glutamate receptor, ionotropic, kainate 4 L homeolog antibody, grik4 antibody, GRIK4 antibody, grik4.L antibody, Grik4 antibody
    背景
    Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability, directly and indirectly, through GABAergic interneurons. Five subunits can assemble to form kainate receptors (KARs): GluR5 (coded by Grik1), GluR6 (coded by Grik2), and GluR7 (coded by Grik3) are the low-affinity subunits, and KA1 and KA2 are the high-affinity subunits. In the adult brain, KARs are located pre- and postsynaptically on pyramidal cells and on interneurons. Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling. KARs have been implicated in numerous psychiatric disorders. Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder. Despite its predicted molecular weight, Grik4 often migrates at a lower molecular weight in SDS-PAGE.Synonyms: EAA1, Excitatory amino acid receptor 1, Glutamate receptor ionotropic kainate 4
    基因ID
    2900
    UniProt
    Q16099
    途径
    Synaptic Membrane
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