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GPAM 抗体 (C-Term)

GPAM 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499910
发货至: 中国
  • 抗原 See all GPAM 抗体
    GPAM (Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 51
    • 17
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 47
    • 4
    克隆类型
    • 50
    • 1
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This GPAM antibody is un-conjugated
    应用范围
    • 41
    • 22
    • 13
    • 13
    • 12
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to GPAT1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    GPAT1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human GPAT1.
    亚型
    IgG
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    Discover our top product GPAM Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    GPAM (Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM))
    别名
    GPAM / GPAT1 (GPAM 产品)
    别名
    Gpam antibody, GPAT antibody, GPAT1 antibody, glycerol-3-phosphate acyltransferase, mitochondrial antibody, GPAM antibody, gpam antibody, Gpam antibody
    背景
    Glycerol-3-phosphate acyltransferase 1 (GPAT1), one of four known GPAT isoforms, is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis, steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets. At least two isoforms of GPAT1 are known to exist.Synonyms: Glycerol-3-phosphate acyltransferase 1, KIAA1560
    基因ID
    57678
    NCBI登录号
    NP_065969
    UniProt
    Q9HCL2
    途径
    Activated T Cell Proliferation
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