CADPS2 抗体 (AA 435-510) (AbBy Fluor® 750)
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- 抗原 See all CADPS2 抗体
- CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
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抗原表位
- AA 435-510
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CADPS2 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CADPS2
- 亚型
- IgG
- Top Product
- Discover our top product CADPS2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
- 别名
- CADPS2 (CADPS2 产品)
- 别名
- RGD1559440 antibody, A230044C21Rik antibody, Caps-2 antibody, Caps2 antibody, Cpd2 antibody, caps antibody, cpd2 antibody, zgc:110135 antibody, calcium dependent secretion activator 2 antibody, Ca2+-dependent activator protein for secretion 2 antibody, Ca++-dependent secretion activator 2 antibody, CADPS2 antibody, Cadps2 antibody, cadps2 antibody
- 背景
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Synonyms: Cadps2, Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, CAPS2, CAPS2_HUMAN.
Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.
- 途径
- Synaptic Vesicle Exocytosis
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