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- 抗原 See all GBL 抗体
- GBL (G protein beta subunit-like (GBL))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GBL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- GbL antibody was raised against a 14 amino acid peptide from near the carboxy-terminus of human GbL.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Human GbL / G beta protein subunit-like Peptide
- 亚型
- IgG
- Top Product
- Discover our top product GBL Primary Antibody
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anti-G protein beta subunit-like (GBL) (AA 1-326) antibody
GBL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 159-220) antibodyGBL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (C-Term) antibodyGBL 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 140-170) antibodyGBL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11669 unconjugated
anti-G protein beta subunit-like (GBL) antibodyGBL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (Middle Region) antibodyGBL 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- GBL (G protein beta subunit-like (GBL))
- 别名
- LST8 / GBL (GBL 产品)
- 别名
- gbl antibody, lts8 antibody, GBL antibody, GbetaL antibody, LST8 antibody, POP3 antibody, WAT1 antibody, 0610033N12Rik antibody, AA409454 antibody, AI505104 antibody, AI851821 antibody, Gbl antibody, fi37e04 antibody, wu:fi37e04 antibody, zgc:55455 antibody, zgc:85668 antibody, MTOR associated protein, LST8 homolog L homeolog antibody, MTOR associated protein, LST8 homolog antibody, MTOR associated protein, LST8 homolog (S. cerevisiae) antibody, mlst8.L antibody, MLST8 antibody, Mlst8 antibody, mlst8 antibody
- 背景
- GbetaL (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors (1). It binds to the kinase domain of TOR (Target of rapamycin, also known as mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors (reviewed in 2). Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation (reviewed in 3). TOR is normally associated with GβL and an additional regulatory protein RAPTOR, allowing TOR to control protein biosynthesis (3). The binding of GβL to TOR stimulates TOR's kinase activity towards downstream proteins such as RPS6K (ribosomal protein S6 kinase) and the translation factor 4E-BP1 which leads to increased protein translation and cell growth (3).Synonyms: G protein beta subunit-like, Gable, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8
- 基因ID
- 64223
- UniProt
- Q9BVC4
- 途径
- PI3K-Akt Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
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