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FAM59A 抗体 (C-Term)

FAM59A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499824
发货至: 中国
  • 抗原 See all FAM59A 抗体
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    抗原表位
    • 15
    • 5
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 21
    克隆类型
    • 21
    多克隆
    标记
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM59A antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    FAM59A antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAM59A.
    亚型
    IgG
    Top Product
    Discover our top product FAM59A Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    FAM59A (Family with Sequence Similarity 59, Member A (FAM59A))
    别名
    FAM59A (FAM59A 产品)
    别名
    C18orf11 antibody, FAM59A antibody, Gm944 antibody, C86169 antibody, Fam59a antibody, mKIAA4238 antibody, fam59a antibody, zgc:55634 antibody, GRB2 associated regulator of MAPK1 subtype 1 antibody, GRB2 associated, regulator of MAPK1 antibody, GAREM1 antibody, Garem1 antibody, garem antibody
    背景
    FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling pathway of the EGF receptor and the tumorigenesis of cells.Synonyms: C18orf11
    基因ID
    64762
    UniProt
    Q9H706
    途径
    EGFR Signaling Pathway
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