GID8/C20orf11 抗体 (AbBy Fluor® 750)
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- 抗原 See all GID8/C20orf11 (GID8) 抗体
- GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GID8/C20orf11 antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TWA1/C20orf11
- 亚型
- IgG
- Top Product
- Discover our top product GID8 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GID8/C20orf11 (GID8) (GID Complex Subunit 8 Homolog (GID8))
- 别名
- C20orf11 (GID8 产品)
- 别名
- C20orf11 antibody, TWA1 antibody, Bwk1 antibody, 2310003C23Rik antibody, C13H20orf11 antibody, GID complex subunit 8 homolog antibody, GID complex subunit 8 antibody, GID8 antibody, Gid8 antibody
- 背景
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Synonyms: Chromosome 20 open reading frame 11, CT011_HUMAN, Protein C20orf11, Twa1, Two hybrid associated protein 1, Two hybrid-associated protein 1 with Ran BP-M, Two hybrid associated protein 1 with RanBPM, Two hybrid-associated protein 1 with RanBPM.
Background: TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2 % of the human genome and contains nearly 63 million bases that encode over 600 genes.
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