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TMC8 抗体 (Center)

TMC8 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499810
发货至: 中国
  • 抗原 See all TMC8 抗体
    TMC8 (Transmembrane Channel-Like 8 (TMC8))
    抗原表位
    • 15
    • 7
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    人, 小鼠, 大鼠
    宿主
    • 42
    克隆类型
    • 42
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMC8 antibody is un-conjugated
    应用范围
    • 34
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to EVER2.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    EVER2 antibody was raised against a 14 amino acid peptide from near the center of human EVER2.
    亚型
    IgG
    Top Product
    Discover our top product TMC8 Primary Antibody
  • 应用备注
    ELISA. Western Blt: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    TMC8 (Transmembrane Channel-Like 8 (TMC8))
    别名
    TMC8 (TMC8 产品)
    别名
    EV2 antibody, EVER2 antibody, EVIN2 antibody, Ever2 antibody, mFLJ00400 antibody, transmembrane channel like 8 antibody, transmembrane channel-like 8 antibody, transmembrane channel-like gene family 8 antibody, TMC8 antibody, Tmc8 antibody
    背景
    Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc. At least three isoforms of EVER2 are known to exist, this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.Synonyms: EVER2, EVIN2, Epidermodysplasia verruciformis protein 2, Transmembrane channel-like protein 8
    基因ID
    147138
    UniProt
    Q8IU68
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