9130013K24Rik antibody, AI840082 antibody, elovl1 antibody, wu:fd20a06 antibody, zgc:56422 antibody, cgpr01 antibody, elovl7 antibody, fi36f02 antibody, wu:fi36f02 antibody, zgc:55879 antibody, ELOVL fatty acid elongase 7 antibody, Elongation of very long chain fatty acids protein 7 antibody, elongation of very long chain fatty acids protein 7 antibody, ELOVL family member 7, elongation of long chain fatty acids (yeast) antibody, ELOVL fatty acid elongase 7b antibody, ELOVL fatty acid elongase 7 L homeolog antibody, ELOVL fatty acid elongase 7a antibody, ELOVL7 antibody, elov7 antibody, Elovl7 antibody, elovl7b antibody, elovl7.L antibody, elovl7a antibody
背景
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes, its expression is regulated by the microRNA miR-219.Synonyms: 3-keto acyl-CoA synthase ELOVL7, Elongation of very long chain fatty acids protein 7