ELOVL6
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 555
应用备注
ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
FACE antibody, FAE antibody, LCE antibody, C77826 antibody, Lce2 antibody, rELO2 antibody, lce antibody, cb618 antibody, zgc:73089 antibody, elovl6 antibody, ELOVL fatty acid elongase 6 antibody, ELOVL family member 6, elongation of long chain fatty acids (yeast) antibody, elongation of very long chain fatty acids protein 6 antibody, elongation of very long chain fatty acids protein 6-like antibody, ELOVL6 antibody, Elovl6 antibody, elovl6 antibody, Tsp_06132 antibody, LOC108710167 antibody
背景
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.Synonyms: Elongation of very long chain fatty acids protein 6, FACE, Fatty acyl-CoA elongase, LCE, Long-chain fatty-acyl elongase, hELO2