ELISA. Western Blot: EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
SWS1 antibody, efhd2 antibody, EFHD2 antibody, MGC131292 antibody, 2600015J22Rik antibody, AA408606 antibody, D4Wsu27e antibody, si:dkey-72l14.9 antibody, wu:fb80e07 antibody, EF-hand domain family member D2 antibody, EF-hand domain family, member D2 antibody, EF-hand domain family member D2 L homeolog antibody, EF hand domain containing 2 antibody, EFHD2 antibody, Efhd2 antibody, efhd2 antibody, efhd2.L antibody
背景
EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.Synonyms: EF-hand domain-containing protein D2, SWS1, Swiprosin 1, Swiprosin-1