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ECSIT 抗体 (C-Term)

ECSIT 适用: 人, 小鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499780
发货至: 中国
  • 抗原 See all ECSIT 抗体
    ECSIT
    抗原表位
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 24
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 24
    • 2
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This ECSIT antibody is un-conjugated
    应用范围
    • 24
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ECSIT antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.
    纯化方法
    Ion exchange chromatography
    免疫原
    Human ECSIT (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product ECSIT Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ECSIT
    别名
    ECSIT (ECSIT 产品)
    别名
    CG10610 antibody, DmECSIT antibody, Dmel\\CG10610 antibody, dECSIT antibody, ECSIT antibody, Sitpec antibody, SITPEC antibody, CG10610 gene product from transcript CG10610-RA antibody, ECSIT signalling integrator antibody, ecsit antibody, ECSIT signalling integrator S homeolog antibody, ECSIT antibody, CpipJ_CPIJ003637 antibody, Ecsit antibody, ecsit.S antibody
    背景
    Activation of NF-?B as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses (reviewed in 1). Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 (2) to kinases such as IRAK (3) and other intermediates such as TNF receptor associated factor (TRAF)-6 (4). ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway (5). Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis (6), indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.Synonyms: ECSIT homolog (Drosophila), Evolutionarily conserved signaling intermediate in Toll pathway, SITPEC, Signaling intermediate in toll pathway evolutionarily conserved, mitochondrial
    基因ID
    51295
    NCBI登录号
    NP_057665
    UniProt
    Q9BQ95
    途径
    TLR signaling, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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