BCL6B 抗体 (AA 141-440) (AbBy Fluor® 750)
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- 抗原 See all BCL6B 抗体
- BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
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抗原表位
- AA 141-440
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL6B antibody is conjugated to AbBy Fluor® 750
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BCL6B
- 亚型
- IgG
- Top Product
- Discover our top product BCL6B Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
- 别名
- BCL6B (BCL6B 产品)
- 别名
- BAZF antibody, ZBTB28 antibody, ZNF62 antibody, Bazf antibody, RGD1563179 antibody, B-cell CLL/lymphoma 6B antibody, B cell CLL/lymphoma 6, member B antibody, B-cell CLL/lymphoma 6, member B antibody, BCL6B antibody, Bcl6b antibody, bcl6b antibody
- 背景
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Synonyms: B cell CLL/lymphoma 6, member B zinc finger protein, B-cell CLL/lymphoma 6, member B zinc finger protein, BAZF, Bcl6 associated zinc finger protein, Bcl6-associated zinc finger protein, ZBTB28, Zinc finger protein 62, ZNF62.
Background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.
- 途径
- BCR Signaling
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