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- 抗原 See all DAD1 抗体
- DAD1 (Defender Against Cell Death 1 (DAD1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- DAD1 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human DAD1.
- 纯化方法
- Ion exchange chromatography
- 免疫原
- Murine DAD1 Peptide
- 亚型
- IgG
- Top Product
- Discover our top product DAD1 Primary Antibody
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anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibody
DAD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibodyDAD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B4-C8 unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-100) antibodyDAD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: 0.5 to 2 μg/mL. Despite its predicted molecular weight, DAD1 migrates at approx. 22 kDa in SDS-PAGE. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- DAD1 (Defender Against Cell Death 1 (DAD1))
- 别名
- DAD1 (DAD1 产品)
- 别名
- NV18456 antibody, dad1 antibody, DAD1 antibody, ost2 antibody, DAD-1 antibody, si:ch211-9d9.5 antibody, OST2 antibody, AI323713 antibody, DEFENDER AGAINST APOPTOTIC DEATH 1 antibody, F3C3.14 antibody, F3C3_14 antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, defender against cell death 1 antibody, hypothetical protein antibody, defender against cell death 1 S homeolog antibody, Defender against death (DAD family) protein antibody, false DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antibody, LOC100115214 antibody, DAD1 antibody, dad1 antibody, CC1G_00458 antibody, CpipJ_CPIJ003512 antibody, PGTG_09898 antibody, Dad1 antibody, dad1.S antibody, ATDAD1 antibody, fdad1 antibody, dad-1 antibody
- 背景
- Defender of cell death 1 (DAD1) was initially discovered in BHK21 cells as a negative regulator of programmed cell death (1), a process important for normal organism development and tissue homeostasis (2). DAD1 was later shown to be a subunit of the mammalian oligosaccharyltransferase complex and is required for its function and structural integrity (3,4). Mice lacking DAD1 express abnormal N-linked glycoproteins and undergo increased apoptotic-associated embryonic death (5,6). Furthermore, overexpression of DAD1 mRNA is seen in some human hepatocellular carcinomas (7), indicating it may also play a role in carcinogenesis. It should be noted that DAD1 is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: DAD-1, OST2, defender against cell death 1, dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1, oligosaccharyl transferase subunit DAD1
- 基因ID
- 1603
- UniProt
- P61803
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