CX3CR1 抗体 (N-Term)
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- 抗原 See all CX3CR1 抗体
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CX3CR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Human CX3CR1 (N-Terminus) Peptide
- 亚型
- IgG
- Top Product
- Discover our top product CX3CR1 Primary Antibody
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- 应用备注
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ELISA. Western Blot: CX3CR1 antibody can be used for detection of CX3CR1 at 1/500 to 1/2000dilution. An approximately 50 kDa band can be detected. Immunohistochemistry. FACS.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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Overexpression of CX3CR1 is associated with cellular metastasis, proliferation and survival in gastric cancer." in: Oncology reports, Vol. 33, Issue 2, pp. 615-24, (2015) (PubMed).
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Overexpression of CX3CR1 is associated with cellular metastasis, proliferation and survival in gastric cancer." in: Oncology reports, Vol. 33, Issue 2, pp. 615-24, (2015) (PubMed).
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- 抗原
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
- 别名
- CX3CR1 / GPR13 (CX3CR1 产品)
- 别名
- CCRL1 antibody, CMKBRL1 antibody, CMKDR1 antibody, GPR13 antibody, GPRV28 antibody, V28 antibody, Rbs11 antibody, C-X3-C motif chemokine receptor 1 antibody, chemokine (C-X3-C motif) receptor 1 antibody, CX3C chemokine receptor 1 antibody, CX3CR1 antibody, Cx3cr1 antibody, LOC100559882 antibody
- 背景
- CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28
- 基因ID
- 1524
- NCBI登录号
- NP_001328
- UniProt
- P49238
- 途径
- Cellular Response to Molecule of Bacterial Origin
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