ELISA. Western Blot: CTRP4 antibody can be used for the detection of CTRP4 at 1 - 2 μg/mL. Ratbrain cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
抗原
C1QTNF4
(Complement C1q Tumor Necrosis Factor-Related Protein 4 (C1QTNF4))
c1qt4 antibody, CTRP4 antibody, ZACRP4 antibody, 0710001E10Rik antibody, 9430004J15Rik antibody, zgc:112213 antibody, C1q and TNF related 4 antibody, C1q and tumor necrosis factor related protein 4 antibody, C1q and TNF related 4 S homeolog antibody, c1qtnf4 antibody, C1QTNF4 antibody, C1qtnf4 antibody, c1qtnf4.S antibody
背景
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of mouse CTRP4 have been reported.Synonyms: CTRP4, Complement C1q tumor necrosis factor-related protein 4