C1QTNF1
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
应用备注
ELISA. Western Blot: CTRP1 antibody can be used for the detection of CTRP1 at 1 μg/mL. Theseproteins are often highly modified post-translationally and migrate in SDS-PAGE atpositions other than their predicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
抗原
C1QTNF1
(C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))
C1QTNF1 antibody, CTRP1 antibody, GIP antibody, ZSIG37 antibody, 1600017K21Rik antibody, Zsig37 antibody, Ctrp1 antibody, zgc:113062 antibody, C1q and tumor necrosis factor related protein 1 antibody, C1q and TNF related 1 antibody, C1QTNF1 antibody, c1qtnf1 antibody, C1qtnf1 antibody
背景
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice (3).Synonyms: CTRP1, Complement C1q tumor necrosis factor-related protein 1, G protein-coupled receptor-interacting protein, GIP