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BIRC2 抗体 (C-Term)

BIRC2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499623
发货至: 中国
  • 抗原 See all BIRC2 抗体
    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
    抗原表位
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 33
    • 4
    • 4
    人, 小鼠
    宿主
    • 29
    • 4
    克隆类型
    • 28
    • 5
    多克隆
    标记
    • 18
    • 6
    • 5
    • 2
    • 1
    • 1
    This BIRC2 antibody is un-conjugated
    应用范围
    • 29
    • 18
    • 17
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    C-IAP antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 c-IAP antibody detects both c-IAP1 and c-IAP2.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human cIAP (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product BIRC2 Primary Antibody
  • 应用备注
    ELISA. Western Blot: cIAP antibody can be used for the detection of c-IAP at 1 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
    别名
    IAP2 / BIRC2 (BIRC2 产品)
    背景
    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases (1 for review). The two isoforms of c-IAP (c-IAP1 and c-IAP2) are structurally related to XIAP, containing 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspasesSynonyms: API1, Baculoviral IAP repeat-containing protein 2, C-IAP1, HIAP-2, HIAP2, IAP homolog B, Inhibitor of apoptosis protein 2, MIHB, RING finger protein 48, RNF48, TNFR2-TRAF-signaling complex protein 2, cIAP1
    基因ID
    329
    NCBI登录号
    NP_001157
    UniProt
    Q13490
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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