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AFAP1L2 抗体 (AbBy Fluor® 680)

AFAP1L2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal AbBy Fluor® 680
产品编号 ABIN4996187
发货至: 中国
  • 抗原 See all AFAP1L2 抗体
    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 21
    • 2
    克隆类型
    • 21
    • 2
    多克隆
    标记
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    This AFAP1L2 antibody is conjugated to AbBy Fluor® 680
    应用范围
    • 22
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    预测反应
    Human,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human AFAP1L2
    亚型
    IgG
    Top Product
    Discover our top product AFAP1L2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
    别名
    AFAP1L2 (AFAP1L2 产品)
    别名
    KIAA1914 antibody, XB130 antibody, AU041783 antibody, C86904 antibody, mKIAA1914 antibody, RGD1310668 antibody, actin filament associated protein 1 like 2 antibody, actin filament associated protein 1-like 2 antibody, AFAP1L2 antibody, Afap1l2 antibody
    背景

    Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.

    Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

    途径
    EGFR Signaling Pathway
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