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5-Methylcytosine 抗体 (AbBy Fluor® 750)

WB, FACS, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN4995770
发货至: 中国
  • 抗原
    5-Methylcytosine
    适用
    请咨询
    宿主
    • 21
    • 9
    • 3
    克隆类型
    • 23
    • 10
    多克隆
    标记
    • 17
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    AbBy Fluor® 750
    应用范围
    • 19
    • 15
    • 12
    • 10
    • 9
    • 8
    • 8
    • 5
    • 5
    • 3
    • 2
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    交叉反应 (详细)
    5 MethylCytosine
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated 5 MethylCytosine
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    5-Methylcytosine
    别名
    5 MethylCytosine
    物质类
    Chemical
    背景

    Synonyms: 5-Methyl Cytidine, 5 m C, 5 mC, 5 me C, 5 Me Cytidine, 5 MeCyd, 5 Methyl Cytidine, 5 MethylCytosine, 5-mC, 5-Me Cytidine, 5-Methyl-Cytosine, 5-MethylCytidine.

    Background: Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.

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