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CARD8 抗体

CARD8 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499535
发货至: 中国
  • 抗原 See all CARD8 抗体
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    适用
    • 38
    • 10
    • 9
    宿主
    • 33
    • 5
    克隆类型
    • 35
    • 3
    多克隆
    标记
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    This CARD8 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    CARD8 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARD8.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Human CARD8 / Cardinal / TUCAN Peptide
    亚型
    IgG
    Top Product
    Discover our top product CARD8 Primary Antibody
  • 应用备注
    ELISA. Immunocytochemistry. Western Blot: CARD8 antibody can be used for detection of CARD8 at 2 μg/mL. K562 cell lysate can be used as Positive Control and a band at approximately 45 kDa canbe detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
    别名
    CARD8 / NDPP1 (CARD8 产品)
    别名
    CARD8 antibody, CARDINAL antibody, DACAR antibody, DAKAR antibody, NDPP antibody, NDPP1 antibody, TUCAN antibody, caspase recruitment domain family, member 8 antibody, caspase recruitment domain-containing protein 8 antibody, caspase recruitment domain family member 8 antibody, CARD8 antibody, LOC718594 antibody
    背景
    Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis (1,2), and caspase-1 and its related proteins ICEBERG and pesudo-ICE (3). Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein (2,4), it has been suggested that it functions as an adaptor molecule regulating caspase-1 and NF-kappaB activation.Synonyms: Apoptotic protein NDPP-1, CARD-inhibitor of NF-kappa-B-activating ligand, CARDINAL, Caspase recruitment domain-containing protein 8, DACAR, KIAA0955, TUCAN, Tumor up-regulated CARD-containing antagonist of CASP9
    基因ID
    22900
    UniProt
    Q9Y2G2
    途径
    Positive Regulation of Endopeptidase Activity
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