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BRSK2 抗体 (C-Term)

BRSK2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499503
发货至: 中国
  • 抗原 See all BRSK2 抗体
    BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
    抗原表位
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    C-Term
    适用
    • 23
    • 20
    • 2
    人, 小鼠
    宿主
    • 30
    • 2
    • 1
    克隆类型
    • 33
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRSK2 antibody is un-conjugated
    应用范围
    • 24
    • 22
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to BRSK2.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    BRSK2 antibody was raised against a 23 amino acid peptide from near the carboxy terminus of human BRSK2.
    亚型
    IgG
    Top Product
    Discover our top product BRSK2 Primary Antibody
  • 应用备注
    ELISA. Western Blot: BRSK2 antibody can be used for detection of BRSK2 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
    别名
    BRSK2 (BRSK2 产品)
    别名
    C11orf7 antibody, PEN11B antibody, SAD1 antibody, SADA antibody, STK29 antibody, BRSK2 antibody, 4833424K13Rik antibody, SAD-A antibody, BR serine/threonine kinase 2 antibody, BRSK2 antibody, Brsk2 antibody
    背景
    BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK2 is expressed in the brain and to a lesser extent in the testes. BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1. More recently, it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis. At least four isoforms of BRSK2 are known to exist.Synonyms: BR serine/threonine-protein kinase 2, C11orf7, HUSSY-12, PEN11B, SAD-A, STK29, Serine/threonine kinase SAD-A, Serine/threonine-protein kinase 29
    基因ID
    9024
    UniProt
    Q8IWQ3
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