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BRSK1 抗体 (C-Term)

BRSK1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499499
发货至: 中国
  • 抗原 See all BRSK1 抗体
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 51
    • 31
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 73
    克隆类型
    • 72
    • 1
    多克隆
    标记
    • 21
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BRSK1 antibody is un-conjugated
    应用范围
    • 47
    • 38
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to BRSK1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    BRSK1 antibody was raised against a 28 amino acid peptide from near the carboxy terminus of human BRSK1.
    亚型
    IgG
    Top Product
    Discover our top product BRSK1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: BRSK1 antibody can be used for detection of BRSK1 at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
    别名
    BRSK1 (BRSK1 产品)
    别名
    BRSK1 antibody, hSAD1 antibody, Gm1100 antibody, SAD-B antibody, SADB antibody, RGD1563268 antibody, Sad-b antibody, BR serine/threonine kinase 1 antibody, BRSK1 antibody, Brsk1 antibody
    背景
    BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.Synonyms: BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B
    基因ID
    84446
    UniProt
    Q8TDC3
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