BRE 抗体 (N-Term)
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- 抗原 See all BRE 抗体
- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to BRCC45.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- BRCC45 antibody was raised against a 18 amino acid peptide from near the amino terminus of human BRCC45.
- 亚型
- IgG
- Top Product
- Discover our top product BRE Primary Antibody
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anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 51-229) antibody
BRE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) antibodyKO Validated BRE 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 94-383) antibodyBRE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (C-Term) antibodyBRE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 9-338) antibodyBRE 适用: 人, 小鼠 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 1-415) antibodyBRE 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (C-Term) antibodyBRE 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 斑马鱼, Cow, 犬, 非洲爪蟾, Bat, 小鸡, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: BRCC45 antibody can be used for detection of BRCC45 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
- 别名
- BRE / BRCC45 (BRE 产品)
- 别名
- brcc4 antibody, brcc45 antibody, BRE antibody, LOC100231620 antibody, BRCC4 antibody, BRCC45 antibody, 6030405P19Rik antibody, AI429776 antibody, B830038C02Rik antibody, im:7141046 antibody, zgc:110368 antibody, BRISC and BRCA1 A complex member 2 antibody, brain and reproductive organ-expressed (TNFRSF1A modulator) antibody, BRISC and BRCA1 A complex member 2 L homeolog antibody, babam2 antibody, BABAM2 antibody, Babam2 antibody, BRE antibody, babam2.L antibody
- 背景
- BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs. Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36. This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage. BRCC45 has also been suggested to function as a death receptor-associated anti-apoptotic protein by inhibiting the BID-induced activation of the mitochondrial apoptotic pathway. Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, suggesting that BRCC45 may promote tumorigenesis when overexpressed. At least three isoforms of BRCC45 are known to exist.Synonyms: BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, BRCC45, BRE, Brain and reproductive organ-expressed protein
- 基因ID
- 9577
- NCBI登录号
- NP_004890
- UniProt
- Q9NXR7
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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