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- 抗原 See all BICD1 抗体
- BICD1 (Bicaudal D Homolog 1 (BICD1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BICD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to BICD1. This antibody will only recognize the larger isoform.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- BICD1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BICD1.
- 亚型
- IgG
- Top Product
- Discover our top product BICD1 Primary Antibody
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anti-Bicaudal D Homolog 1 (BICD1) (AA 1-70) antibody
BICD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: BICD1 antibody can be used for detection of BICD1 at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- BICD1 (Bicaudal D Homolog 1 (BICD1))
- 别名
- BICD1 (BICD1 产品)
- 别名
- BICD antibody, B830009D06Rik antibody, mKIAA4125 antibody, bicaudal D homolog 1 L homeolog antibody, BICD cargo adaptor 1 antibody, bicaudal D homolog 1 (Drosophila) antibody, bicd1.L antibody, BICD1 antibody, Bicd1 antibody
- 背景
- BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. At least two isoforms of BICD1 are known to exist.Synonyms: Bic-D1, Protein bicaudal D homolog 1
- 基因ID
- 636
- NCBI登录号
- NP_001705
- UniProt
- Q96G01
- 途径
- Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location
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