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BICD1 抗体 (C-Term)

BICD1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499455
发货至: 中国
  • 抗原 See all BICD1 抗体
    BICD1 (Bicaudal D Homolog 1 (BICD1))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 13
    • 1
    克隆类型
    • 14
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BICD1 antibody is un-conjugated
    应用范围
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to BICD1. This antibody will only recognize the larger isoform.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    BICD1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BICD1.
    亚型
    IgG
    Top Product
    Discover our top product BICD1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: BICD1 antibody can be used for detection of BICD1 at 0.5 - 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    BICD1 (Bicaudal D Homolog 1 (BICD1))
    别名
    BICD1 (BICD1 产品)
    别名
    BICD antibody, B830009D06Rik antibody, mKIAA4125 antibody, bicaudal D homolog 1 L homeolog antibody, BICD cargo adaptor 1 antibody, bicaudal D homolog 1 (Drosophila) antibody, bicd1.L antibody, BICD1 antibody, Bicd1 antibody
    背景
    BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells. At least two isoforms of BICD1 are known to exist.Synonyms: Bic-D1, Protein bicaudal D homolog 1
    基因ID
    636
    NCBI登录号
    NP_001705
    UniProt
    Q96G01
    途径
    Ribonucleoprotein Complex Subunit Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, Maintenance of Protein Location
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