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ARL6IP1 抗体 (C-Term)

ARL6IP1 适用: 人, 小鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499337
发货至: 中国
  • 抗原 See all ARL6IP1 抗体
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    抗原表位
    • 14
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    • 1
    C-Term
    适用
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    人, 小鼠
    宿主
    • 34
    • 4
    克隆类型
    • 36
    • 2
    多克隆
    标记
    • 18
    • 4
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    This ARL6IP1 antibody is un-conjugated
    应用范围
    • 25
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    • 3
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.
    纯化方法
    Ion exchange chromatography
    免疫原
    Human ARMER / ARL6IP / AIP1 (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product ARL6IP1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: ARMER antibody can be used for detection of ARMER at 0.5 to 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    别名
    ARL6IP1 (ARL6IP1 产品)
    别名
    arl6ip antibody, MGC56593 antibody, zgc:56593 antibody, zgc:77873 antibody, ARL6IP antibody, aip1 antibody, armer antibody, ARL6IP1 antibody, MGC85055 antibody, MGC139614 antibody, DKFZp459O112 antibody, AIP1 antibody, ARMER antibody, AIP-6 antibody, AL022945 antibody, AU042858 antibody, Aip-1 antibody, Arl6ip antibody, C85138 antibody, mKIAA0069 antibody, ADP-ribosylation factor-like 6 interacting protein 1 antibody, ADP ribosylation factor like GTPase 6 interacting protein 1 antibody, ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog antibody, ADP-ribosylation factor like GTPase 6 interacting protein 1 antibody, arl6ip1 antibody, ARL6IP1 antibody, arl6ip1.L antibody, Arl6ip1 antibody
    背景
    Apoptosis is important for normal development and tissue homeostasis. It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA (1). Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12 (2), other caspases such as caspase-9 are also thought to be activated following ER stress (3). Recently, ARMER, a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis. Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity (3), although the mechanism for this remains unkown. It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, KIAA0069
    基因ID
    23204
    UniProt
    Q15041
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