AP2M1 抗体 (C-Term)
Quick Overview for AP2M1 抗体 (C-Term) (ABIN499285)
抗原
See all AP2M1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to AP2M1.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- AP2M1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human AP2M1.
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亚型
- IgG
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anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 97-383) antibody
AP2M1 适用: 人, 大鼠, 犬 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 97-383) antibodyAP2M1 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 298-435) antibodyAP2M1 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 4F1B2 unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 136-435) antibodyAP2M1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 1-435) antibodyAP2M1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (Internal Region) antibodyAP2M1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 134-433) antibodyAP2M1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) antibodyAP2M1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (Center) antibodyAP2M1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) (AA 60-278) antibodyAP2M1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot: AP2M1 antibody can be used for detection of AP2M1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))
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背景
- The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.Synonyms: AP-2 mu-2 chain, Adaptin-mu2, CLAPM1, Clathrin assembly protein complex 2 medium chain, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP5, HA2 50 kDa subunit, KIAA0109, Plasma membrane adaptor AP-2 50 kDa protein
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基因ID
- 1173
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NCBI登录号
- NP_004059
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UniProt
- Q96CW1
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
抗原
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