TUBA1A 抗体 (N-Term)
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- 抗原 See all TUBA1A (Tuba1a) 抗体
- TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This TUBA1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to Alpha-tubulin.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin.
- 亚型
- IgG
- Top Product
- Discover our top product Tuba1a Primary Antibody
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- 应用备注
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ELISA. Western Blot: Tubulin antibody can be used for detection of Tubulin at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).
: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." in: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).
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Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).
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- 抗原
- TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))
- 别名
- alpha Tubulin / TUBA1A / TUBA3 (Tuba1a 产品)
- 背景
- Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.Synonyms: Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-1A chain, Tubulin alpha-3 chain
- 基因ID
- 7846
- UniProt
- Q71U36
- 途径
- Microtubule Dynamics, M Phase
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