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AIPL1 抗体 (Center)

AIPL1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499251
发货至: 中国
  • 抗原 See all AIPL1 抗体
    AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))
    抗原表位
    • 15
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 41
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 32
    • 9
    克隆类型
    • 34
    • 7
    多克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIPL1 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 12
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to AIPL1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Aipl1 antibody was raised against a 18 amino acid peptide near the center of the human Aipl1.
    亚型
    IgG
    Top Product
    Discover our top product AIPL1 Primary Antibody
  • 应用备注
    ELISA. Western Blot: Aipl1 antibody can be used for detection of Aipl1 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))
    别名
    AIPL1 (AIPL1 产品)
    别名
    AIPL1 antibody, lca4 antibody, aipl2 antibody, AIPL2 antibody, LCA4 antibody, A930007I01Rik antibody, aryl hydrocarbon receptor interacting protein like 1 antibody, aryl hydrocarbon receptor-interacting protein-like 1 antibody, AIPL1 antibody, aipl1 antibody, Aipl1 antibody
    背景
    Aipl1 was initially identified as a protein implicated in Leber congenital amaurosis (LCA), an autosomal recessive disorder thought to be caused by the abnormal development of photoreceptors. Aipl1 is a tetratricopeptide repeat protein that is highly homologous to ARA9, a protein involved in the HSP90-mediated nuclear translocation and transactivation of the aryl hydrocarbon receptor. Aipl1 has also been found to function as part of a chaperone heterocomplex, interacting with Hsp90 and Hsp70. Aipl1 also associates with the cell cycle regulator NUB1. It is thought that Aipl1 cooperates with Hsp70 but not Hsp90 to suppress the formation of NUB1 inclusions, and these interactions are necessary in the normal photoreceptor maturation, as mutations that lead to LCA also compromise the interactions with the Hsp chaperones. At least three isoforms of Aipl1 are known to exist.Synonyms: Aryl-hydrocarbon-interacting protein-like 1
    基因ID
    23746
    NCBI登录号
    NP_055151
    UniProt
    Q9NZN9
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