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AIFM3 抗体 (N-Term)

AIFM3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499241
发货至: 中国
  • 抗原 See all AIFM3 抗体
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    抗原表位
    • 1
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    N-Term
    适用
    • 15
    • 5
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    • 2
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 14
    • 1
    克隆类型
    • 15
    多克隆
    标记
    • 8
    • 1
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    This AIFM3 antibody is un-conjugated
    应用范围
    • 5
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    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to AIFM3.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    AIFM3 antibody was raised against a 16 amino acid peptide from near the amino terminus of human AIFM3.
    亚型
    IgG
    Top Product
    Discover our top product AIFM3 Primary Antibody
  • 应用备注
    ELISA. Western Blot: AIFM3 antibody can be used for the detection of AIFM3 at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))
    Abstract
    AIFM3 产品
    别名
    nfrl-A antibody, MGC84340 antibody, AIFM3 antibody, LOC100150876 antibody, 2810401C16Rik antibody, AI840249 antibody, Aifl antibody, RGD1306028 antibody, AIFL antibody, apoptosis inducing factor, mitochondria associated 3 L homeolog antibody, apoptosis inducing factor, mitochondria associated 3 antibody, apoptosis-inducing factor, mitochondrion-associated 3 antibody, aifm3.L antibody, AIFM3 antibody, aifm3 antibody, Aifm3 antibody
    背景
    Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.Synonyms: AIFL, Apoptosis-inducing factor 3
    基因ID
    150209
    UniProt
    Q96NN9
    途径
    Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis
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