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- 抗原 See all FYB 抗体
- FYB (FYN-Binding Protein (FYB))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FYB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes ADAP (C-term).
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- A 20 amino acid peptide from near the carboxy terminus of Human ADAP
- 亚型
- IgG
- Top Product
- Discover our top product FYB Primary Antibody
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anti-FYN-Binding Protein (FYB) antibody
FYB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (C-Term) antibodyFYB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 678-829) antibodyFYB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (Internal Region) antibodyVerified FYB 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 646-695) antibodyFYB 适用: 人, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (AA 39-88) antibodyFYB 适用: 人, 小鼠, 马, Pig, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-FYN-Binding Protein (FYB) (N-Term) antibodyFYB 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: ADAP antibody can be used for detection of ADAP at 0.5 - 1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FYB (FYN-Binding Protein (FYB))
- 别名
- FYN-Binding Protein (FYB 产品)
- 别名
- fyb antibody, ADAP antibody, PRO0823 antibody, SLAP-130 antibody, B630013F22Rik antibody, FYB-120/130 antibody, Slap130 antibody, p120/130 antibody, p120/p130 antibody, RGD1563421 antibody, FYN-binding protein antibody, FYN binding protein 1 antibody, FYN binding protein antibody, fyb antibody, FYB1 antibody, Fyb antibody, Fyb1 antibody
- 背景
- The adhesion and degranulation adaptor protein (ADAP) was initially identified as a molecular adapter that couples T cell receptor (TCR) stimulation to the avidity of integrins governing T cell adhesion. TCR stimulation promotes the formation of a multi-protein complex containing CARMA1, MALT1, and BCL-10, which through the association of ADAP, ultimately activates the NF-kappaB family of transcription factors. More recent experiments have shown that ADAP controls optimal T cell proliferation, cytokine production, and expression of the Bcl-2 family member Bcl-x(L), suggesting that ADAP regulates T cell activation by promoting antigen-dependent T cell-antigen presenting cell (APC) activation. At least three isoforms of ADAP are known to exist.Synonyms: Adhesion and degranulation promoting adaptor protein, FYB-120/130, FYN-T-binding protein, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130
- 基因ID
- 2533
- NCBI登录号
- NP_955367
- UniProt
- O15117
- 途径
- TCR Signaling, Protein targeting to Nucleus
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