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ADAM10 抗体 (C-Term)

ADAM10 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499211
发货至: 中国
  • 抗原 See all ADAM10 抗体
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 65
    • 29
    • 29
    • 1
    • 1
    • 1
    宿主
    • 54
    • 11
    • 2
    • 1
    克隆类型
    • 48
    • 20
    多克隆
    标记
    • 30
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM10 antibody is un-conjugated
    应用范围
    • 42
    • 15
    • 14
    • 14
    • 13
    • 13
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    ADAM10 antibody was raised against a peptide corresponding to amino acids 732 to 748 of human ADAM10. This sequence is identical to those of bovine and rat origins and differs from that of mouse ADAM10 by one amino acid (2,4).
    纯化方法
    Ion exchange chromatography
    免疫原
    Human ADAM10 (C-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product ADAM10 Primary Antibody
  • 应用备注
    ELISA. Western Blot: ADAM10 can be used for detection of ADAM10 at 1: 500 to 1: 2000 dilution. Anapproximately 85 kDa band can be detected, which may represent precursor. Immunocytochemistry: 2,0 μg/mL
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    别名
    CD156c / ADAM10 (ADAM10 产品)
    别名
    ADAM10 antibody, Adam10 antibody, adam10 antibody, wu:fc03d12 antibody, ad10 antibody, cd156c antibody, kuz antibody, kuzbanian antibody, madm antibody, xadam10 antibody, ADAM-10 antibody, ADAM 10 antibody, AD10 antibody, CD156c antibody, HsT18717 antibody, MADM antibody, 1700031C13Rik antibody, LOC100219653 antibody, zgc:64203 antibody, ADAM metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10a antibody, ADAM metallopeptidase domain 10 S homeolog antibody, a disintegrin and metallopeptidase domain 10 antibody, ADAM metallopeptidase domain 10b antibody, ADAM10 antibody, Adam10 antibody, adam10a antibody, adam10.S antibody, adam10b antibody
    背景
    Proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha, notch and its ligand delta (1-3). The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively, (1,2,4). ADAM10 mRNA is expressed in a variety of human and bovine tissues (1,4).Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease
    基因ID
    102
    NCBI登录号
    NP_001101
    UniProt
    O14672
    途径
    Notch Signaling, EGFR Signaling Pathway
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