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AAK1 抗体 (N-Term)

Name: AAK1 抗体 (N-Term)
SKU: ABIN499183
Availability: OutOfStock

AAK1 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Aak1 in A-20 lysate with AP30003PU-N Aak1 antibody at (A) 1 and (B) 2 μg/ml. (AAK1 抗体 (N-Term))

Immunocytochemistry of Aak1 in A-20 cells with AP30003PU-N Aak1 antibody at 5 μg/ml. (AAK1 抗体 (N-Term))

2 images

产品编号 ABIN499183

发货至: 中国

Datasheet as PDF

抗原 See all AAK1 抗体

AAK1 (AP2 associated kinase 1 (AAK1))
抗原表位
15

9

8

6

6

6

6

4

2

2

2

2

2

1

1

1

1

1

1
N-Term
适用
42

38

12

4

4

4

3

3

3

2

1

1
人, 小鼠, 大鼠
宿主
62

4

1
兔
Compatible Secondaries
克隆类型
64

3
多克隆
标记
33

5

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This AAK1 antibody is un-conjugated
应用范围
42

30

20

13

13

7

6

4

3

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

特异性

This antibody recognizes AAK1 near the amino terminus.

纯化方法

Affinity chromatography purified via peptide column

免疫原

A 20 amino acid peptide near the amino terminus of the uman Aak1

亚型

IgG

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AAK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B10 unconjugated

anti-AP2 associated kinase 1 (AAK1) (AA 274-465) antibody
AAK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (C-Term) antibody
AAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (N-Term) antibody
AAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (AA 301-400) antibody
AAK1 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (N-Term) antibody
AAK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) antibody
AAK1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (Internal Region) antibody
AAK1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (Internal Region) antibody
Verified AAK1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-AP2 associated kinase 1 (AAK1) (AA 593-642) antibody
AAK1 适用: 人, 小鼠, 大鼠, 马, 猴, 兔, 犬, 小鸡 WB 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA. Western Blot: Aak1 antibody can be used for detection of Aak1 at 1 - 2 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
缓冲液

PBS containing 0.02 % Sodium Azide as preservative

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

AAK1 (AP2 associated kinase 1 (AAK1))

别名

AAK1 (AAK1 产品)

别名

5530400K14Rik antibody, 9630042K20 antibody, AU067724 antibody, AU067726 antibody, BC028270 antibody, C79663 antibody, D6Ertd245e antibody, R75501 antibody, mKIAA1048 antibody, RGD1563580 antibody, aak1 antibody, si:dkey-261l11.5 antibody, AP2 associated kinase 1 antibody, uncharacterized protein FLJ45252 antibody, AP2 associated kinase 1b antibody, AAK1 antibody, Aak1 antibody, LOC100512341 antibody, aak1b antibody

背景

AP2-associated protein kinase 1 (Aak1) is a member of the Ark1/Prk1 subfamily of Ser/Thr protein kinases that are thought to regulate endocytosis by phosphorylating the accessory endocytic components. Aak1 interacts with and phosphorylates the mu2 subunit of the AP-2 complex, which promotes binding of the AP-2 to tyrosine based (Yxxf) internalization motif-containing receptors and subsequent receptor endocytosis. At least two isoforms of Aak1 are known to exist, the longer isoform contains an extended carboxy-terminus that contains an additional clathrin-binding domain. Overexpression of this long isoform or Aak1 depletion by RNA interference impairs transferrin recycling from the early/sorting endosome, suggesting that Aak1 functions at multiple steps of the endosomal pathway by regulating transferrin internalization and its recycling back to the plasma membrane.Synonyms: AP2-associated protein kinase 1, KIAA1048

基因ID

22848

NCBI登录号

NP_055726

UniProt

Q2M2I8