Serotonin Receptor 3B 抗体 (Internal Region)
-
- 抗原 See all Serotonin Receptor 3B (HTR3B) 抗体
- Serotonin Receptor 3B (HTR3B)
-
抗原表位
- Internal Region
-
适用
- 人
-
宿主
- 山羊
-
克隆类型
- 多克隆
-
标记
- This Serotonin Receptor 3B antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- C-SNYLQTQDQT DQQE
- 特异性
- This antibody detects Serotonin receptor 3B (Internal).
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- 免疫原
- Peptide from the internal region (near C-terminus) of the protein sequence according to NP_006019.1
- Top Product
- Discover our top product HTR3B Primary Antibody
-
-
- 应用备注
-
Peptide ELISA: 1: 16000 (limit dilution). Western blot: 1-3 μg/mL. Approx 51 kDa band observed in Human Brain (Cerebral Cortex,Hippocampus and Amygdala) lysates (calculated MW of 50.1 kDa according toNP_006019.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.
-
- 抗原
- Serotonin Receptor 3B (HTR3B)
- Abstract
- HTR3B 产品
- 别名
- HTR3B antibody, 5-HT3B antibody, 5-hydroxytryptamine receptor 3B antibody, 5-hydroxytryptamine (serotonin) receptor 3B antibody, HTR3B antibody, Htr3b antibody
- 背景
- There are 4 main groups of receptors which bind the neurotransmitter serotonin: 5HT1, 5HT2 5HT3 and 5HT4. 5HT3B receptor is subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin). This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Through interactions with these receptors, serotonin is able to exert a wide variety of physiological functions. 5HT3 receptors are cation-selective transmitter-gated ion channels. 5HT3B receptor mutations have been implicated in depression.Synonyms: 5-HT3-B, 5-HT3B, 5-hydroxytryptamine receptor 3B
- 基因ID
- 9177
- NCBI登录号
- NP_006019
- UniProt
- O95264
- 途径
- Synaptic Membrane
-