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Anoctamin 5 抗体 (C-Term)

ANO5 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499159
发货至: 中国
  • 抗原 See all Anoctamin 5 (ANO5) 抗体
    Anoctamin 5 (ANO5)
    抗原表位
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 798-828, C-Term
    适用
    • 15
    • 9
    • 1
    人, 小鼠
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This Anoctamin 5 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 7
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    Recognizes ANO5 (C-term).
    纯化方法
    Protein A Chromatography followed by peptide affinity purification
    免疫原
    Synthetic peptide -KLH conjugated between 798~828 amino acids from the C-terminal region of Human ANO5. Genename: ANO5
    亚型
    Ig Fraction
    Top Product
    Discover our top product ANO5 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Anoctamin 5 (ANO5)
    别名
    ANO5 (ANO5 产品)
    别名
    gdd1 antibody, tmem16e antibody, MGC82557 antibody, TMEM16E antibody, ano5 antibody, si:dkey-261m9.4 antibody, GDD1 antibody, LGMD2L antibody, 9330162L24 antibody, Gdd1 antibody, Tmem16e antibody, anoctamin 5 L homeolog antibody, anoctamin 5 antibody, anoctamin 5a antibody, ano5.L antibody, ANO5 antibody, ano5a antibody, ano5 antibody, Ano5 antibody
    背景
    ANO5 is a member of the anoctamin family of transmembrane proteins. This protein is likely a calcium activated chloride channel. Defects in ANO5 are the cause of gnathodiaphyseal dysplasia (GDD), also known as osteogenesis imperfecta with unusual skeletal lesions or gnathodiaphyseal sclerosis. GDD is a rare skeletal syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbone. Patients experience frequent bone fractures caused by trivial accidents in childhood, however the fractures heal normally without bone deformity. The jaw lesions replace the tooth-bearing segments of the maxilla and mandible with fibrous connective tissues, including various amounts of cementum-like calcified mass, sometimes causing facial deformities. Patients also have a propensity for jaw infection and often suffer from purulent osteomyelitis-like symptoms, such as swelling of and pus discharge from the gums, mobility of the teeth, insufficient healing after tooth extraction and exposure of the lesions into the oral cavity.Synonyms: Anoctamin-5, GDD1, Gnathodiaphyseal dysplasia 1 protein, TMEM16E, Transmembrane 16E
    基因ID
    203859
    NCBI登录号
    NP_001136121
    UniProt
    Q75V66
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