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- 抗原 See all VASP 抗体
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VASP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of VASP protein. (region surrounding Ala232)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography using epitope-specific immunogen
- 纯度
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product VASP Primary Antibody
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anti-Vasodilator-Stimulated phosphoprotein (VASP) antibody
VASP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-100) antibodyVASP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibodyVASP 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibodyVASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibodyVASP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-380) antibodyVASP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibodyVASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer238) antibodyVASP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-380) antibodyVASP 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 78-114), (N-Term) antibodyVASP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- 别名
- VASP (VASP 产品)
- 背景
- The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopeni,a eczem,a defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP has been identified as a downstream effector of Cdc42 and has been implicated in Actin polymerization and cytoskeletal organization. A distantly related protein, VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with Actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.Synonyms: Vasodilator-stimulated phosphoprotein
- 分子量
- approx. 48 kDa
- 基因ID
- 7408
- NCBI登录号
- NP_003361
- UniProt
- P50552
- 途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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