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Cytokeratin 13 抗体

KRT13 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498524
发货至: 中国
  • 抗原 See all Cytokeratin 13 (KRT13) 抗体
    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 62
    • 23
    • 1
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    克隆类型
    • 56
    • 31
    多克隆
    标记
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    This Cytokeratin 13 antibody is un-conjugated
    应用范围
    • 60
    • 32
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Cytokeratin 13 protein. (region surrounding Glu282)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product KRT13 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))
    别名
    Cytokeratin 13 (KRT13 产品)
    别名
    krt13 antibody, CK13 antibody, K13 antibody, Ka13 antibody, Krt-1.13 antibody, Krt1-13 antibody, ck13 antibody, k13 antibody, keratin 24 antibody, keratin 13 antibody, keratin 13, type I S homeolog antibody, krt24 antibody, KRT13 antibody, Krt13 antibody, krt13.S antibody, k13 antibody
    背景
    Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with Cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epitheli,a and is characterized by the presence of soft, white and spongy plaques in the oral mucosa.Synonyms: CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13
    分子量
    approx. 50 kDa
    基因ID
    3860
    NCBI登录号
    NP_002265
    UniProt
    P13646
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