-
- 抗原 See all SYT1 抗体
- SYT1 (Synaptotagmin I (SYT1))
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SYT1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody antibody detects endogenous levels of Synaptotagmin protein.
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product SYT1 Primary Antibody
-
anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (pSer309) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 301-523) antibodySYT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western Blots: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- SYT1 (Synaptotagmin I (SYT1))
- 别名
- Synaptotagmin-1 (SYT1 产品)
- 背景
- Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25 kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP- 2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including α- and γ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exo-cytosis by competing with SNAP 25 and syntaxins for VAMP binding.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
- 分子量
- approx. 60 kDa
- 基因ID
- 6857
- NCBI登录号
- NP_001129277
- UniProt
- P21579
- 途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
-
You are here:
