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WEE1 抗体 (AA 202-230)
WEE1
适用: 人, 小鼠
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
WEE1抗体详情
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抗原
See all WEE1 抗体
WEE1
(WEE1 Homolog (S. Pombe) (WEE1))
抗原表位
All epitopes for WEE1 抗体
AA 202-230
适用
All reactivities for WEE1 抗体
人, 小鼠
宿主
All hosts for WEE1 抗体
兔
克隆类型
All clonalities for WEE1 抗体
多克隆
标记
All conjugates for WEE1 抗体
This WEE1 antibody is un-conjugated
应用范围
All applications for WEE1 抗体
Western Blotting (WB), ELISA
交叉反应 (详细)
Expected species reactivity: Rat
纯化方法
Antigen affinity purified
免疫原
A portion of amino acids 202-230 from the mouse protein was used as the immunogen for this Wee1 antibody.
亚型
Ig Fraction
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Discover our top product WEE1 Primary Antibody
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使用细节
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应用备注
Titration of the Wee1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
In 1X PBS, pH 7.4, with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the Wee1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
WEE1目标详情
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抗原
WEE1
(WEE1 Homolog (S. Pombe) (WEE1))
别名
Wee1 (WEE1 产品 )
别名
WEE1A antibody, WEE1hu antibody, ATWEE1 antibody, F22D16.3 antibody, F22D16_3 antibody, WEE1 kinase homolog antibody, WEE1-KINASE antibody, WEE1 antibody, Xe-Wee1B antibody, XeWee1B antibody, wee1-b antibody, wee1a antibody, wee2-a antibody, xe-wee1a antibody, xwee1 antibody, wee1 antibody, wee1b antibody, wee1hu antibody, xwee2 antibody, GB19689 antibody, Wee1A antibody, fa20h03 antibody, wu:fa20h03 antibody, zgc:136514 antibody, WEE1 G2 checkpoint kinase antibody, Wee1 kinase antibody, WEE1-like kinase antibody, WEE1 G2 checkpoint kinase S homeolog antibody, wee1 homolog antibody, WEE1 homolog 2 antibody, wee1-like protein kinase antibody, WEE 1 homolog 1 (S. pombe) antibody, M phase inhibitor protein kinase Wee1 antibody, WEE1 antibody, Wee1 antibody, wee1.S antibody, wee1-a antibody, wee2 antibody, LOC551677 antibody, wee1 antibody
背景
Wee1 may act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur (By similarity).
UniProt
P47810
途径
Cell Division Cycle , Mitotic G1-G1/S Phases , M Phase
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