TXNIP 抗体 (AA 1-30)
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- 抗原 See all TXNIP 抗体
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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抗原表位
- AA 1-30
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TXNIP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
- 纯化方法
- Antigen affinity purified
- 免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this TXNIP antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TXNIP Primary Antibody
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- 应用备注
- Titration of the TXNIP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the TXNIP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- 别名
- TXNIP (TXNIP 产品)
- 背景
- TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. [UniProt]
- UniProt
- Q9H3M7
- 途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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