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TLR5 抗体 (AA 825-856)

TLR5 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029173
发货至: 中国
  • 抗原 See all TLR5 抗体
    TLR5 (Toll-Like Receptor 5 (TLR5))
    抗原表位
    • 13
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 825-856
    适用
    • 103
    • 69
    • 34
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 93
    • 17
    • 2
    克隆类型
    • 87
    • 25
    多克隆
    标记
    • 47
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR5 antibody is un-conjugated
    应用范围
    • 77
    • 38
    • 32
    • 14
    • 12
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Purified
    免疫原
    A portion of amino acids 825-856 from the mouse protein was used as the immunogen for this TLR5 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TLR5 Primary Antibody
  • 应用备注
    Titration of the TLR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the TLR5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    TLR5 (Toll-Like Receptor 5 (TLR5))
    别名
    TLR5 (TLR5 产品)
    别名
    SLEB1 antibody, TIL3 antibody, TLR-5 antibody, sleb1 antibody, til3 antibody, tlr-5 antibody, tlr5 antibody, toll like receptor 5 antibody, toll-like receptor 5 antibody, toll like receptor 5 L homeolog antibody, toll-like receptor 5b antibody, TLR5 antibody, Tlr5 antibody, tlr5.L antibody, tlr-5 antibody, tlr5b antibody
    背景
    TLR5, a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents. It also plays a role in mediating detection of bacterial flagellins. TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues. The TLR5 gene lies in a locus that is associated with susceptibility to Salmonella. Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA). The strain MOLF/Ei is highly susceptible to the infection, has an unique TLR5 haplotype and a lower expression of TRL5.
    UniProt
    Q9JLF7
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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