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TLK2 抗体 (AA 141-171)

This anti-TLK2 antibody is a 兔 多克隆 antibody detecting TLK2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN3029189
发货至: 中国

Quick Overview for TLK2 抗体 (AA 141-171) (ABIN3029189)

抗原

See all TLK2 抗体
TLK2 (Tousled-Like Kinase 2 (TLK2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TLK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 141-171

    纯化方法

    Purified

    免疫原

    A portion of amino acids 141-171 from the human protein was used as the immunogen for this TLK2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the TLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TLK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TLK2 (Tousled-Like Kinase 2 (TLK2))

    别名

    TLK2

    背景

    TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

    UniProt

    Q86UE8
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