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TICAM1 抗体 (AA 115-143)
TICAM1
适用: 人, 小鼠
WB, ELISA
宿主: 兔
Polyclonal
unconjugated
TICAM1抗体详情
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抗原
See all TICAM1 抗体
TICAM1
(Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
抗原表位
All epitopes for TICAM1 抗体
AA 115-143
适用
All reactivities for TICAM1 抗体
人, 小鼠
宿主
All hosts for TICAM1 抗体
兔
克隆类型
All clonalities for TICAM1 抗体
多克隆
标记
All conjugates for TICAM1 抗体
This TICAM1 antibody is un-conjugated
应用范围
All applications for TICAM1 抗体
Western Blotting (WB), ELISA
纯化方法
Antigen affinity purified
免疫原
A portion of amino acids 115-143 from the human protein was used as the immunogen for this TICAM1 antibody.
亚型
Ig Fraction
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Discover our top product TICAM1 Primary Antibody
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使用细节
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应用备注
Titration of the TICAM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the TICAM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
TICAM1目标详情
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抗原
TICAM1
(Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
别名
TICAM1 (TICAM1 产品 )
别名
IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody
背景
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
UniProt
Q8IUC6
途径
TLR signaling , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Toll-Like Receptors Cascades
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