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SOCS4 抗体 (AA 227-254)

SOCS4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029046
发货至: 中国
  • 抗原 See all SOCS4 抗体
    SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
    抗原表位
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 227-254
    适用
    • 34
    • 3
    • 1
    • 1
    宿主
    • 29
    • 4
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    This SOCS4 antibody is un-conjugated
    应用范围
    • 32
    • 22
    • 12
    • 10
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
    亚型
    Ig Fraction
  • 应用备注
    Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SOCS4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
    别名
    SOCS4 (SOCS4 产品)
    背景
    SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
    UniProt
    Q8WXH5
    途径
    JAK/STAT Signaling, EGFR Signaling Pathway
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