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SMAD4 抗体 (AA 400-428)

SMAD4 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032608
发货至: 中国
  • 抗原 See all SMAD4 抗体
    SMAD4 (SMAD Family Member 4 (SMAD4))
    抗原表位
    • 13
    • 11
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-428
    适用
    • 89
    • 43
    • 37
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 78
    • 11
    • 1
    克隆类型
    • 64
    • 26
    多克隆
    标记
    • 56
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD4 antibody is un-conjugated
    应用范围
    • 61
    • 37
    • 32
    • 23
    • 22
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    交叉反应 (详细)
    Expected species reactivity: Mouse, Rat, Bovine, Pig
    纯化方法
    Purified
    免疫原
    A portion of amino acids 400-428 from the human protein was used as the immunogen for this SMAD4 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SMAD4 Primary Antibody
  • 应用备注
    Titration of the SMAD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SMAD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SMAD4 (SMAD Family Member 4 (SMAD4))
    别名
    SMAD4 (SMAD4 产品)
    背景
    In muscle physiology, SMAD4 plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity). [UniProt]
    UniProt
    Q13485
    途径
    Cell Division Cycle, Chromatin Binding, Autophagy
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